People Who Are Immunocompromised | CDC – CDC

Know how to protect yourself and what to do if you get sick
As of January 26, 2023, EVUSHELDTM is not currently authorized for emergency use because it is unlikely to be active against the majority of SARS-CoV-2 variants circulating in the United States.
Some people who are immunocompromised (have a weakened immune system) are more likely to get sick with COVID-19 or be sick for a longer period. People can be immunocompromised either due to a medical condition or from receipt of immunosuppressive medications or treatments.
Examples of medical conditions or treatments that may result in moderate to severe immunocompromise include but are not limited to:
Talk to your healthcare provider if you have another medical condition or are on medication that may not be reflected above.
If you or someone you live or spend time with is immunocompromised, it is important to have a COVID-19 plan to protect yourself from infection and prepare for what to do if you get sick. Information on this page can help you build a COVID-19 plan for preventing, diagnosing, and treating COVID, so you know what to do and can act quickly if you’re exposed, develop symptoms, or test positive and when COVID-19 levels are increasing in your community.
COVID-19 vaccines are effective at protecting people—especially those who are up to date— from getting seriously ill, being hospitalized, and even dying. As with vaccines for other diseases, you are protected best when you stay up to date with your COVID-19 vaccines. The people you live or spend time with can help protect you and themselves by staying up to date on their COVID-19 vaccines too.
You are up to date with your COVID-19 vaccines when you have received all doses in the primary series and all boosters recommended for you, when eligible. Since your immune response to COVID-19 vaccination may not be as strong as in people who are not immunocompromised, you have different recommendations for COVID-19 vaccines, including boosters. Learn more about COVID-19 vaccine recommendations for people who are moderately or severely immunocompromised.
To find COVID-19 vaccine locations near you: Search, text your ZIP code to 438829, or call 1-800-232-0233.
Even if you stay up to date on COVID-19 vaccines, taking multiple prevention steps can provide additional layers of protection from COVID-19.
It’s important to be prepared and know what to do if you get sick with COVID-19. Don’t delay seeking medical care. Be prepared by understanding the following steps:
Effective treatments are now widely available and free, and you may be eligible.
If you have COVID-19, oral antiviral treatments are available for people who are more likely to get very sick. Learn more about COVID-19 treatment.
Don’t delay: Treatment must be started right away to be effective. Talk to your healthcare provider about what treatment options are best for you.
Antiviral treatments may help your body fight COVID-19 by stopping the SARS-CoV-2 virus (the virus that causes COVID-19) from multiplying in your body or by lowering the amount of the virus within your body. You can get a prescription from your healthcare provider or a Test to Treat location. Oral antivirals can be taken at home and must be given within 5 days after the first symptoms of COVID-19 appear.
Some people with COVID-19 who are immunocompromised or are receiving immunosuppressive treatment may benefit from a treatment called convalescent plasma.  Your healthcare provider can help decide whether this treatment is right for you.
Make a COVID-19 plan now so you’re prepared. Consider the ways you will protect yourself and how to be prepared if you get sick with COVID-19. Include how you will adjust your plan if the COVID-19 situation changes in your community.
Your plan should include:
Share your COVID-19 plan with your family, friends, and healthcare providers so they can support your prevention and preparation steps. Consider how others may help you if you get sick and identify the supplies you may need. Be sure to stick to your treatment plans, your routine healthcare appointments, and have all your prescriptions filled. Plan for options for work, childcare, and other responsibilities that may cause stress if you were to become sick.
COVID-19 remains a major health concern and this can be stressful to manage. Understanding what you can do to protect yourself and what to do if you get sick can help minimize that stress. Take as many steps as you can to prevent COVID-19 and get treated quickly if you have COVID-19.
Put together your COVID-19 plan so you have all the information you need on hand if you get sick with COVID-19. Download, edit and save, and share your plan with your family, friends, and healthcare provider.
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